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Case studies

Transforming respiratory care: New partnership model aligns national ambition with local action

Summary The Respiratory Transformation Partnership (RTP) is a landmark national collaboration to improve care for people with asthma, chronic obstructive pulmonary disease (COPD) and other respiratory conditions. It is receiving funding totalling £10 million over the next two years from the Office for Life Sciences (OLS), NHS England (NHSE) and four industry partners: AstraZeneca, Chiesi […]

Case study categories: Respiratory National Care close to home Digital Prevention

Assessing a real-time 3D image analysis tool in the mechanical thrombectomy stroke pathway

Summary An evaluation of an image analysis tool has demonstrated its potential in the mechanical thrombectomy pathway following stroke. This included input from clinicians, patients and carers. Further analysis is needed to support widespread adoption. What is the challenge? Mechanical thrombectomy (MT) is a specialist procedure to treat acute ischaemic stroke. It’s highly time-sensitive and […]

Case study categories: Stroke Local Digital Prevention Supporting innovators

Health economic evaluation of novel drug delivery agent in breast cancer brain metastases

Summary Breast cancer brain metastases (BCBM) occur when cancer cells spread from the breast to the brain and represent a substantial clinical and economic challenge for the NHS. mutTNF (mutant tumour necrosis factor) is a novel therapy designed to temporarily open the blood–brain barrier at sites of brain metastases, improving the delivery of treatments to […]

Case study categories: Breast cancer Local Supporting innovators

Supporting early rule-out of infection in urgent and emergency care: A feasibility study of a rapid molecular diagnostic device

Summary Health Innovation Oxford and Thames Valley (HIOTV) performed a feasibility study of InfectiClear Rapid, a rapid molecular diagnostic designed to support early rule out of infection in emergency and acute care settings, developed by Presymptom Health. Using HIOTV’s Lean Assessment Process (LAP) methodology, semi-structured interviews were conducted with clinicians across nine NHS trusts to […]

Case study categories: Local Sepsis Care close to home Digital Prevention Supporting innovators

Placental growth factor-based testing to rule out pre-eclampsia

Summary Quick, accurate blood tests for pre-eclampsia (PE) are contributing to safer pregnancies and better outcomes for tens of thousands of pregnant women and their unborn babies every year. More accurate diagnosis reduces the need for admission and enables a clearer focus on women needing closer monitoring. The pandemic underlined the importance of safe and […]

Case study categories: Preeclampsia National Prevention

A feasibility study of a machine learning-based risk stratification tool for enhancing the rheumatology referral pathway

Summary An evaluation of a machine learning-based risk stratification tool assessed the acceptance and potential barriers to adopting this tool, designed to support the rheumatology referral pathway. The study involved gathering insights from GPs, rheumatology registrars and rheumatology consultants. The findings of our feasibility study will assist RMD-Health developers in finalising the functionality of the […]

Case study categories: Supporting innovators Rheumatology Local Digital

Improving outcomes following stroke through increased access to mechanical thrombectomy

Summary More patients are getting the right treatment in the right place more quickly leading to better outcomes following a stroke thanks to a five-year collaborative programme led by Health Innovation Oxford and Thames Valley (HIOTV) supporting the deployment of artificial intelligence (AI) in stroke diagnosis. This approach has led to more stroke patients receiving […]

Case study categories: Stroke National Digital Supporting innovators